{
  "_id": "6ac4ba6bf511ae58c09a0836",
  "Package": "SMUT",
  "Type": "Package",
  "Title": "Multi-SNP Mediation Intersection-Union Test",
  "Version": "1.3",
  "Author": "Wujuan Zhong",
  "Maintainer": "Wujuan Zhong <zhongwujuan@gmail.com>",
  "Description": "Testing the mediation effect of multiple SNPs on an\noutcome through a mediator.",
  "LazyData": "true",
  "License": "GPL (>= 2)",
  "NeedsCompilation": "yes",
  "Packaged": {
    "Date": "2026-10-06 09:00:35 UTC",
    "User": "root"
  },
  "VignetteBuilder": "knitr",
  "Repository": "https://wjzhong.r-universe.dev",
  "Date/Publication": "2020-11-23 01:46:24 UTC",
  "RemoteUrl": "https://github.com/wjzhong/smut",
  "RemoteRef": "HEAD",
  "RemoteSha": "492c1c65537bad701282b93f34371d921dbf6189",
  "_user": "wjzhong",
  "_type": "src",
  "_file": "SMUT_1.3.tar.gz",
  "_fileid": "https://r2.ropensci.org/a9460455d5e0153721823e4276c013d30ec9468cd97cd01fc50da7d02c81a82e",
  "_filesize": 131206,
  "_sha256": "a9460455d5e0153721823e4276c013d30ec9468cd97cd01fc50da7d02c81a82e",
  "_expires": "2027-01-14T09:07:52.000Z",
  "_created": "2026-10-06T09:00:35.000Z",
  "_published": "2026-10-06T09:07:55.436Z",
  "_jobs": [
    {
      "job": 112191230241,
      "time": 146,
      "config": "linux-devel-arm64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11400972345"
    },
    {
      "job": 112191230297,
      "time": 134,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11401255408"
    },
    {
      "job": 112191230263,
      "time": 132,
      "config": "linux-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11400259509"
    },
    {
      "job": 112191230321,
      "time": 124,
      "config": "linux-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11400289497"
    },
    {
      "job": 112191230221,
      "time": 197,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "11401215632"
    },
    {
      "job": 112191230180,
      "time": 287,
      "config": "macos-oldrel-x86_64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "11401053674"
    },
    {
      "job": 112191230168,
      "time": 246,
      "config": "macos-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11400349537"
    },
    {
      "job": 112191230231,
      "time": 340,
      "config": "macos-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": ""
    },
    {
      "job": 112189843851,
      "time": 209,
      "config": "source",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11401047899"
    },
    {
      "job": 112191230060,
      "time": 87,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "11400508647"
    },
    {
      "job": 112191230286,
      "time": 395,
      "config": "windows-devel-arm64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11400453559"
    },
    {
      "job": 112191230461,
      "time": 156,
      "config": "windows-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11400194639"
    },
    {
      "job": 112191230285,
      "time": 111,
      "config": "windows-oldrel-x86_64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "11400819209"
    },
    {
      "job": 112191230261,
      "time": 363,
      "config": "windows-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11400852977"
    },
    {
      "job": 112191230360,
      "time": 100,
      "config": "windows-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11401210543"
    }
  ],
  "_host": "GitHub-Actions",
  "_buildurl": "https://github.com/r-universe/wjzhong/actions/runs/37439581363",
  "_status": "success",
  "_upstream": "https://github.com/wjzhong/smut",
  "_commit": {
    "id": "492c1c65537bad701282b93f34371d921dbf6189",
    "author": "Wujuan Zhong <zhongwujuan@gmail.com>",
    "committer": "Wujuan Zhong <zhongwujuan@gmail.com>",
    "message": "update vignettes\n",
    "time": 1606095984
  },
  "_maintainer": {
    "name": "Wujuan Zhong",
    "email": "zhongwujuan@gmail.com",
    "login": "wjzhong",
    "description": "",
    "uuid": 34694327
  },
  "_distro": "resolute",
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 2.10",
      "role": "Depends"
    },
    {
      "package": "Rcpp",
      "role": "LinkingTo"
    },
    {
      "package": "RcppEigen",
      "role": "LinkingTo"
    },
    {
      "package": "Rcpp",
      "version": ">= 0.12.14",
      "role": "Imports"
    },
    {
      "package": "SKAT",
      "role": "Imports"
    },
    {
      "package": "MASS",
      "role": "Imports"
    },
    {
      "package": "knitr",
      "role": "Suggests"
    },
    {
      "package": "rmarkdown",
      "role": "Suggests"
    }
  ],
  "_owner": "wjzhong",
  "_selfowned": true,
  "_usedby": 2,
  "_updates": [],
  "_tags": [],
  "_stars": 1,
  "_contributors": [
    {
      "user": "wjzhong",
      "count": 5,
      "uuid": 34694327
    }
  ],
  "_userbio": {
    "uuid": 34694327,
    "type": "user",
    "name": "wjzhong",
    "followers": 3
  },
  "_downloads": {
    "count": 617,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/SMUT"
  },
  "_mentions": 1,
  "_devurl": "https://github.com/wjzhong/smut",
  "_searchresults": 33,
  "_topics": [
    "cpp"
  ],
  "_rbuild": "4.6.1",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/manual.pdf",
    "extra/readme.html",
    "extra/readme.md",
    "extra/SMUT.html"
  ],
  "_homeurl": "https://github.com/wjzhong/smut",
  "_realowner": "wjzhong",
  "_cranurl": true,
  "_releases": [
    {
      "version": "1.0",
      "date": "2018-10-08"
    },
    {
      "version": "1.0.1",
      "date": "2019-04-08"
    },
    {
      "version": "1.1",
      "date": "2019-09-24"
    }
  ],
  "_exports": [
    "eigenMapMatMult",
    "Generalized_Testing_coefficient_of_mediator",
    "GSMUT",
    "SMUT",
    "Testing_coefficient_of_mediator"
  ],
  "_datasets": [
    {
      "name": "Genotype_data",
      "title": "Example genotype data for SMUT",
      "object": "Genotype_data",
      "class": [
        "matrix",
        "array"
      ],
      "fields": [],
      "rows": 100,
      "table": true,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "eigenMapMatMult",
      "title": "Matrix multiplication using RcppEigen",
      "topics": [
        "eigenMapMatMult"
      ]
    },
    {
      "page": "Generalized_Testing_coefficient_of_mediator",
      "title": "Testing coefficient of mediator in the outcome model for an outcome following an exponential family distribution or a survival outcome",
      "topics": [
        "Generalized_Testing_coefficient_of_mediator"
      ]
    },
    {
      "page": "Genotype_data",
      "title": "Example genotype data for SMUT",
      "topics": [
        "Genotype_data"
      ]
    },
    {
      "page": "GSMUT",
      "title": "Generalized Multi-SNP Mediation Intersection-Union Test",
      "topics": [
        "GSMUT"
      ]
    },
    {
      "page": "SMUT",
      "title": "Multi-SNP Mediation Intersection-Union Test",
      "topics": [
        "SMUT"
      ]
    },
    {
      "page": "Testing_coefficient_of_mediator",
      "title": "Testing coefficient of mediator in the outcome model",
      "topics": [
        "Testing_coefficient_of_mediator"
      ]
    }
  ],
  "_readme": "https://github.com/wjzhong/smut/raw/HEAD/README.md",
  "_rundeps": [
    "lattice",
    "MASS",
    "Matrix",
    "Rcpp",
    "RcppEigen",
    "RSpectra",
    "SKAT",
    "SPAtest"
  ],
  "_sysdeps": [
    {
      "shlib": "libstdc++",
      "package": "libstdc++6",
      "source": "gcc",
      "version": "16-20260322-1ubuntu1",
      "name": "c++",
      "homepage": "http://gcc.gnu.org/",
      "description": "GNU Standard C++ Library v3"
    }
  ],
  "_vignettes": [
    {
      "source": "SMUT.Rmd",
      "filename": "SMUT.html",
      "title": "SMUT Package: Testing the Mediation Effect of Multiple SNPs on an Outcome Through a Mediator",
      "author": "Wujuan Zhong",
      "engine": "knitr::rmarkdown",
      "headings": [
        "0. Installation",
        "1. Overview",
        "2. Multi-SNP Mediation Intersection-Union Test (SMUT) : Testing mediation effects of multiple SNPs on a continuous outcome through a continuous mediator",
        "2.1 Mediator model",
        "2.2 Outcome model",
        "2.3 Testing $\\beta$ in the mediator model and $\\theta$ in the outcome model",
        "2.4 Example of running R function SMUT",
        "2.5 References",
        "3. Generalized Multi-SNP Mediation Intersection-Union Test (GSMUT) : Testing mediation effects of multiple SNPs on a continuous, binary, count or time-to-event outcome through a continuous mediator",
        "3.1 Mediator model",
        "3.2 Outcome model",
        "3.2.1  For a continuous, binary or count outcome",
        "3.2.2  For a time-to-event outcome",
        "3.3 Testing $\\beta$ in the mediator model and $\\theta$ in the outcome model",
        "3.4 Example of running R function GSMUT",
        "3.5 Options for the parameter outcome_type in the GSMUT function",
        "3.6 References"
      ],
      "created": "2020-11-22 12:18:58",
      "modified": "2020-11-23 01:46:24",
      "commits": 4
    }
  ],
  "_score": 4.99563519459755,
  "_indexed": true,
  "_nocasepkg": "smut",
  "_universes": [
    "wjzhong"
  ],
  "_binaries": [
    {
      "r": "4.6.1",
      "os": "mac",
      "version": "1.3",
      "date": "2026-09-06T06:34:26.000Z",
      "arch": "x86_64",
      "commit": "492c1c65537bad701282b93f34371d921dbf6189",
      "fileid": "https://r2.ropensci.org/369a291976471dd0defc9d8f9ad3965984108a61cd3af70e17184155a1cf811f",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wjzhong/actions/runs/34016533268"
    },
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.3",
      "date": "2026-10-06T09:02:53.000Z",
      "distro": "resolute",
      "arch": "aarch64",
      "commit": "492c1c65537bad701282b93f34371d921dbf6189",
      "fileid": "https://r2.ropensci.org/7c77af81e827663a0731430ff26987cb463e5f6e52495de93ea121219c39477d",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wjzhong/actions/runs/37439581363"
    },
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.3",
      "date": "2026-10-06T09:02:33.000Z",
      "distro": "resolute",
      "arch": "x86_64",
      "commit": "492c1c65537bad701282b93f34371d921dbf6189",
      "fileid": "https://r2.ropensci.org/82692cd73f5d02f7cb228ecb49e6785aaecae96e8d4b2b1a10d53ce072aa5ede",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wjzhong/actions/runs/37439581363"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "1.3",
      "date": "2026-10-06T09:02:40.000Z",
      "distro": "resolute",
      "arch": "aarch64",
      "commit": "492c1c65537bad701282b93f34371d921dbf6189",
      "fileid": "https://r2.ropensci.org/dd3b6a51fd3a75090bc32d12b78d2968502de5965b88b9ee3a4ed3b9a4fdf0d5",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wjzhong/actions/runs/37439581363"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "1.3",
      "date": "2026-10-06T09:02:27.000Z",
      "distro": "resolute",
      "arch": "x86_64",
      "commit": "492c1c65537bad701282b93f34371d921dbf6189",
      "fileid": "https://r2.ropensci.org/c7566d2d239d4a6d02309293289337a6e4a658e4efe11d51934d41a48855ec4b",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wjzhong/actions/runs/37439581363"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.3",
      "date": "2026-10-06T09:03:06.000Z",
      "arch": "aarch64",
      "commit": "492c1c65537bad701282b93f34371d921dbf6189",
      "fileid": "https://r2.ropensci.org/57515a65d762d2c43d922fdb12978bdf9ddf21497976985bb76bcdd4e8a48fba",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wjzhong/actions/runs/37439581363"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.3",
      "date": "2026-10-06T09:04:22.000Z",
      "arch": "x86_64",
      "commit": "492c1c65537bad701282b93f34371d921dbf6189",
      "fileid": "https://r2.ropensci.org/a48ad98f473b8d7d2368c10dab2ec826c2bf2240384a891a33f8178018a682a0",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wjzhong/actions/runs/37439581363"
    },
    {
      "r": "4.6.1",
      "os": "mac",
      "version": "1.3",
      "date": "2026-10-06T09:03:27.000Z",
      "arch": "aarch64",
      "commit": "492c1c65537bad701282b93f34371d921dbf6189",
      "fileid": "https://r2.ropensci.org/a94a9bf5030e6e89a0a09bd13218a87dd3b6bcd71ad1686003f9bacb2d67869a",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wjzhong/actions/runs/37439581363"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.3",
      "date": "2026-10-06T09:02:17.000Z",
      "arch": "emscripten",
      "commit": "492c1c65537bad701282b93f34371d921dbf6189",
      "fileid": "https://r2.ropensci.org/48b6a1190b1f5472ae4d9f797c7faedb7b7447eedd704f2252af1cb2b1ae9f81",
      "status": "success",
      "buildurl": "https://github.com/r-universe/wjzhong/actions/runs/37439581363"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.3",
      "date": "2026-10-06T09:06:15.000Z",
      "arch": "aarch64",
      "commit": "492c1c65537bad701282b93f34371d921dbf6189",
      "fileid": "https://r2.ropensci.org/41da4780ecdb000d36944b71a6bb4b9f4e5b6a18ed090583e6c6b4fe028cc0db",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wjzhong/actions/runs/37439581363"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.3",
      "date": "2026-10-06T09:01:53.000Z",
      "arch": "x86_64",
      "commit": "492c1c65537bad701282b93f34371d921dbf6189",
      "fileid": "https://r2.ropensci.org/a6ab1cc888377b5d58a14cbe5f129f5f44d66ec102ac66897f2a5a827a8d415d",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wjzhong/actions/runs/37439581363"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "1.3",
      "date": "2026-10-06T09:01:43.000Z",
      "arch": "x86_64",
      "commit": "492c1c65537bad701282b93f34371d921dbf6189",
      "fileid": "https://r2.ropensci.org/5daa1899d0ca47a5afacb0ec456a122c39ffcce16ef3af33fdbbd5489d5c4dde",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wjzhong/actions/runs/37439581363"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "1.3",
      "date": "2026-10-06T09:05:40.000Z",
      "arch": "aarch64",
      "commit": "492c1c65537bad701282b93f34371d921dbf6189",
      "fileid": "https://r2.ropensci.org/2ef725622a568a13176d675ed56b82d7dc2a5c6dbb99dc9b8b798dea02786b59",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wjzhong/actions/runs/37439581363"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "1.3",
      "date": "2026-10-06T09:01:43.000Z",
      "arch": "x86_64",
      "commit": "492c1c65537bad701282b93f34371d921dbf6189",
      "fileid": "https://r2.ropensci.org/b4b843627e5d98d8559020511a327d2ba17ac608f39e464f5bd4fb085067f951",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/wjzhong/actions/runs/37439581363"
    }
  ]
}